Policosanol is a natural supplement derived from sugar cane. It is a mixture of eight higher primary aliphatic alcohols isolated and purified from sugar cane wax. Policosanol promotes healthy platelet function and helps to maintain cholesterol levels that are already within the normal range.1-14 Animal and human studies have also shown that policosanol is an antioxidant.15-19 When used in long-term clinical trials, policosanol was well tolerated and safe.5,15,20,21
MicroActive Policosanol increases absorption by reducing particle size less than 10 microns thereby promoting more efficient transport through the digestive track and cell walls. In addition, the proprietary mix of polymers in MicroActive Policosanol slows the release rate allowing for absorption over a longer time period. Evidence supports the claim that this combination of greater absorption and sustained release creates a more uniform absorption from subject-to-subject, improving the probability that all consumers will benefit from the active.
References
1. Am J Physiol Heart Circ Physiol. 2001 Jun;280(6):H2616-22.2. Am J Physiol. 1995 Dec.;269(6 Pt 2);H2155-61.3. Med Pregl. 2006 Mar-Apr;59(3-4):143-7.4. Am J Epidemiol. 1996 May 1; 143(9):845-59.5. Br J Nutr. 2007 Nov;98(5):960-8.
6. EMBO Rep. 2006 Mar;7(3):276-82.
7. Med Hypotheses. 2004;62(5):819-24.
8. Am J Physiol Regul Integr Comp Physiol. 2004 Jan;286(1):R182-8.
9. J Mol Cell Cardiol. 1984 Sep;16(9):863-6.
10. Surg Res. 1989 Feb;46(2):157-62.
11. Ann West Med Surg. 1951;5:825-9.
12. Ann West Med Surg. 1951;5:830-55.
13. Ann West Med Surg. 1951;5:856-62.
14. JAMA. 1951;145:1232-6.
15. Am J Dig Dis. 1952;19:381-4.
16. Mol Genet Metab. 2006 Jul;88(3):201-7.
17. Biochemistry. 1999 Oct 19;38(42):13991-8.
18. Greene, R. C. 1996. Biosynthesis of methionine, p. 542-560. In F. C. Neidhardt, R. Curtiss III, J. L. Ingraham, E. C. C. Lin, K. B. Low, B. Magasanik, W. S. Reznikoff, M. Riley, M. Schaechter, and H. E. Umbarger (ed.), Escherichia coli and Salmonella: cellular and molecular biology, 2nd ed. ASM Press, Washington, DC.
19. J Nutr. 2003 Dec;133(12):4135-8.
20. J Nutr. 2003 May;133(5):1291-5.
21. Am J Clin Nutr. 2002 Nov;76(5):961-7.
